This paper investigated whether learner?s personality might have effects on uses of Web-based Hypermedia Systems, which have been used in most electronic learning (e-Learning) environments. The results of this paper implied that personality features of individual learners would dictate the usefulness of adaptive hypermedia systems (AHSs), and in turn, it indicates that the evaluation of e-Learning systems should embody this account for an effective design of AHSs.